Sunday, November 1st, 2009. 1:00 pm @ Lucas Oil Stadium. (FOX)
This game sends the 49ers to Indianapolis to face the Colts. The 49ers defense will have a long day trying contain the Colts passing attack. Peyton Manning and Reggie Wayne will connect for multiple touchdowns and the Colts will win this one easily.
The 49ers lost to Houston 24-21 as a 3-point underdog in Week 7. The combined score went OVER the posted over/under total (44.5). Alex Smith passed for 206 yards with three touchdowns and an interception for San Francisco, while Vernon Davis caught seven passes for 93 yards and three touchdowns. San Francisco is 4-2 SU in its last 6 games when playing Indianapolis and the total has gone UNDER in 4 of San Francisco’s last 6 games on the road.
The Colts defeated St. Louis 42-6 as a 14.5-point favorite in Week 7. The combined score went OVER the posted over/under total (45). Peyton Manning passed for 235 yards with three touchdowns for Indianapolis, while Reggie Wayne caught seven passes for 83 yards and a touchdown in the win.
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